{"id":20793,"date":"2022-01-20T12:16:12","date_gmt":"2022-01-20T12:16:12","guid":{"rendered":"https:\/\/pr.asianetpakistan.com\/?p=85551"},"modified":"2022-01-20T12:16:12","modified_gmt":"2022-01-20T12:16:12","slug":"uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human","status":"publish","type":"post","link":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/","title":{"rendered":"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human"},"content":{"rendered":"<h5 style=\"text-align: right;\">UAB announces the first clinical-grade transplant of gene-edited pig kidneys into brain-dead human<\/h5>\n<div>\n<div style=\"width: 310px\" class=\"wp-caption alignright\"><a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/NewsRoom\/AttachmentNg\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/en&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw2BjbZt_xd5dZDJEsUSFVbe\"  rel=\"noreferrer\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png\" alt=\"\" width=\"300\" height=\"168\" \/><\/a><\/p>\n<p class=\"wp-caption-text\">A doppler probe is used to assess blood flow inside the right porcine (pig) kidney after transplantation into the brain-dead recipient.Hands left to right: Katie Stegner, Dr. Babak Orandi, M.D., Ph.D. (holding the probe), Jayme Locke, M.D. (holding the kidney)Photo taken by Jeff Myers, UAB<\/p>\n<\/div>\n<\/div>\n<div>\n<p><u>NEWS HIGHLIGHTS<\/u><\/p>\n<\/div>\n<p><strong>UAB researchers have achieved several world\u2019s firsts with pig-to-human kidney transplant:<\/strong><\/p>\n<ul>\n<li>First peer-reviewed\/<a href=\"https:\/\/www.google.com\/url?q=https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajt.16930&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw3rIyy0FfA1S--kbEQd4jKn\"  rel=\"nofollow noreferrer\">published<\/a>\u00a0study of a genetically modified pig kidney transplanted into the body of a brain-dead human recipient<\/li>\n<li>First such study on a pig-to-human kidney transplant using genetically modified kidneys with 10 key gene edits that may make the kidneys suitable for direct clinical-grade therapeutic use in humans<\/li>\n<li>First validation of a UAB-developed test for compatibility before xenotransplant<\/li>\n<li>First peer-reviewed\/published study to establish brain death as a viable preclinical human model<\/li>\n<\/ul>\n<p>Notably, the study was designed and conducted to meet standards directly comparable to those that would apply to a Phase I clinical trial and mirrored \u2014 as much as possible \u2014 every step of a conventional transplant between humans. Importantly, this study included removing the human brain-dead recipient\u2019s native kidneys before replacing them with genetically modified pig kidneys.<\/p>\n<p><strong>UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human<\/strong><\/p>\n<ul>\n<li>First peer-reviewed study of its kind\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ajt.16930&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw3rIyy0FfA1S--kbEQd4jKn\"  rel=\"nofollow noreferrer\">published<\/a>\u00a0in the scientific literature<\/li>\n<li>Positive outcomes pave the way to new options to supply critically needed organs<\/li>\n<li><a href=\"https:\/\/www.google.com\/url?q=https:\/\/uab.box.com\/s\/atlvt54ai54hzkkdofbl8iy09qu9jfm2&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw2GS794Qf0ypq29azlfevIL\"  rel=\"nofollow noreferrer\">Media assets: photos, animations, graphics, video interviews, b-roll<\/a><\/li>\n<li><em>Media availability:<\/em>\n<ul>\n<li><em>Virtual News Conference on Thursday, Jan. 20 at 8:30 a.m.\u00a0<\/em><a href=\"https:\/\/www.google.com\/url?q=https:\/\/uab.zoom.us\/meeting\/register\/tZMudOGqrTosGddeASMxovwA0VE26Wqsz5x8&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw34ijlBIRVYz2_lfKkhPNKv\"  rel=\"nofollow noreferrer\"><em>Click here to register<\/em><\/a><em>.<\/em><\/li>\n<li><em>The\u00a0<\/em><a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.uab.edu\/news\/journalists\/studio\/&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw33WPOttVEZFXQoUkCO5F22\"  rel=\"nofollow noreferrer\"><em>UAB News Studio<\/em><\/a><em>\u00a0is available for live or taped interviews with UAB experts.<\/em><\/li>\n<\/ul>\n<\/li>\n<li><em>Read this story and more at\u00a0<\/em><a href=\"https:\/\/www.google.com\/url?q=http:\/\/go.uab.edu\/xenotransplant&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw3rj9fQgVL5vX2_9LStIgM4\"  rel=\"nofollow noreferrer\"><strong>go.uab.edu\/xenotransplant<\/strong><\/a>.<\/li>\n<\/ul>\n<p>BIRMINGHAM, Ala., Jan. 20, 2022 (GLOBE NEWSWIRE) &#8212; The\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DKyOTwNy4t-7mAYyRWSs_Pj0_VxrFWONUGM__qc9L0EUvygjAtRHUMuJxTs_vy9rSkr5mxYGni2UgYoCFrZ9SWSjAKBihVRqD_h6rQtWuq6I%3D&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw0q96gDBi-diERCfp1ODrw0\"  rel=\"nofollow noreferrer\">University of Alabama at Birmingham<\/a>\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DwF3xEG_Vh16lw5QuWps2O24iFiOpS4VhB9M5Kx4JJLfZ28mIvsCv8cDVnsCv_PWEI82PBz0rQtexxDtTUSb8K4FMJt3Lv09H93pXkXRor67n_dCDQfmYc45yR4n6Bu1d&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw3ovX51lps8NjivFOu6tkbg\"  rel=\"nofollow noreferrer\">Marnix E. Heersink School of Medicine<\/a>\u00a0announces today the first peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual, replacing the recipient\u2019s native kidneys. These positive results demonstrate how xenotransplantation could address the worldwide organ shortage crisis.<\/p>\n<p>In the study\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DoghK4Z5XGFGOtJ3j6mSv_rKj2xodgCTmp4cMkU9n6amtal15dtB0AF3Hnky2vmHCXDRBE8RgcqaIWaz1gxgoPlTD1G6FDa3NoQMF6rmUBJYni9Uohs8hitD2MdoQDMCi&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw1hZlLtvcz4veBAVlMASue2\"  rel=\"nofollow noreferrer\">published<\/a>\u00a0in the American Journal of Transplantation, UAB researchers tested the first human preclinical model for transplanting genetically modified pig kidneys into humans. The study recipient had two genetically modified pig kidneys transplanted in his abdomen after his native kidneys were removed. The organs were procured from a genetically modified pig at a pathogen-free facility.<\/p>\n<p>\u201cAlong with our partners, we have made significant investments in xenotransplantation for almost a decade hoping for the kinds of results published today,\u201d said Selwyn Vickers, M.D., dean of the UAB Heersink School of Medicine and CEO of the UAB Health System and UAB\/Ascension St. Vincent\u2019s Alliance. \u201cToday\u2019s results are a remarkable achievement for humanity and advance xenotransplant into the clinical realm. With this study, our research teams have also demonstrated that the decedent model has significant potential to propel the xenotransplantation field forward.\u201d<\/p>\n<p>For the first time, the pig kidneys transplanted were taken from pigs that had been genetically modified with 10 key gene edits that may make the kidneys suitable for transplant into humans. This process demonstrates the long-term viability of the procedure and how such a transplant might work in the real world. The transplanted kidneys filtered blood, produced urine and, importantly, were not immediately rejected. The kidneys remained viable until the study was ended, 77 hours after transplant.<\/p>\n<p>\u201cThis game-changing moment in the history of medicine represents a paradigm shift and a major milestone in the field of xenotransplantation, which is arguably the best solution to the organ shortage crisis,\u201d said Jayme Locke, M.D., director of the\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DBATJB_xj_A87KdmuKGFXhsaxPUBjE654GTFSoA9ObkdMPiRG1XlTtxNOhncb1VLS7zYU27Jh8oVJysUWwcDZbLoOOv-nsOK4KSST_h71BOuuK_cUaAzazgY5u9-RXssf&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw10Rr1601eeXCzZFEffvQoF\"  rel=\"nofollow noreferrer\">Comprehensive Transplant Institute<\/a>\u00a0in\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DuLl11DCJyySqeflb-5j3AeXHbu4rbaRZHAl5EsPp7mR_8x-ceip2_gbqPGuUoPS4TY_hR8ryB81uj8A8JrJy-WFGHtozD0KWmDZScaxuyRh6mTkt5NKIV2bYhwkcBPqF&amp;source=gmail-html&amp;ust=1642767299193000&amp;usg=AOvVaw1KKQPnQ-X5VbxEnmx1FI7P\"  rel=\"nofollow noreferrer\">UAB\u2019s Department of Surgery<\/a>\u00a0and lead surgeon for the study. \u201cWe have bridged critical knowledge gaps and obtained the safety and feasibility data necessary to begin a clinical trial in living humans with end-stage kidney failure disease.\u201d<\/p>\n<p>Gene editing in pigs to reduce immune rejection has made organ transplants from pigs to humans possible, which could offer help to thousands of people who face organ failure, disease or injury. The natural lifespan of a pig is 30 years, they are easily bred and can have organs of similar size to humans.<\/p>\n<p>Genetically modified pig kidneys have been extensively tested in non-human primates. In addition to testing in non-human primates, evaluating genetically modified pig kidneys in a human preclinical model research may provide important information about the potential safety and efficacy of kidneys in human transplant recipients, including in clinical trials.<\/p>\n<p>\u201cThis human preclinical model is a way to evaluate the safety and feasibility of the pig-to-non-human primate model, without risk to a living human,\u201d Locke added. \u201cOur study demonstrates that major barriers to human xenotransplantation have been surmounted, identifies where new knowledge is needed to optimize xenotransplantation outcomes in humans, and lays the foundation for the establishment of a novel preclinical human model for further study.\u201d<\/p>\n<p>This effort is supported by biotechnology pioneer\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DmamORhZYLcPkQr5UlgXCCEu_O-mHRGLXhZLV9m2NubZ0csTRexklHbUzsRwneil1J-TTlvOhWR3UDzGNI7Rn7WHYvwlrsz0_zeuxofxUSrQ%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw3fYuM4KXRjpI5e1_L8pNyj\"  rel=\"nofollow noreferrer\">United Therapeutics Corporation<\/a>, which\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DyfPWE1z4TxKRnxrEq2IXLeSLGlhnvFhFnzQbXirXENWyM1riXOtVFVRV504GFLC717q1ZyX2IMWUGtm2hktPSTQrIHttUcq7WrihGDgphMDQw5gInu58_Dka9WBKVRmaPt8UKyBW1sQepMgmF8AdjepkAvERKu6ElTtU801z2YrqyY81hMfVnT6CR85Soo47&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw3yCS8efMJRVjl1WqwC_kVY\"  rel=\"nofollow noreferrer\">awarded<\/a>\u00a0a grant to UAB to launch the innovative xenotransplantation program. Revivicor, Inc., a subsidiary of United Therapeutics, provided the genetically modified pig that was the source of the investigational xenotransplant kidneys called UKidney\u2122.<\/p>\n<p>\u201cAll of us at Revivicor are in awe of the historic achievements at UAB with our investigational 10-gene xenokidney, or UKidney,\u201d said David Ayares, Ph.D., Chief Scientific Officer of Revivicor and a trailblazing genetic engineer since his early work cloning the world\u2019s first pigs and the first alpha-Gal knockout pigs. \u201cWe feel confident that this UKidney may turn out to be a life-saving solution for thousands of people on dialysis, subject to successful completion of our clinical trials and achievement of FDA approval in the next several years.\u201d<\/p>\n<p><strong>About the study<\/strong><br \/>\nThe peer-reviewed research is a study of ambitious scope and great significance, given that more than 800,000 Americans are living with kidney failure. Most never make it to the waiting list, and far too few human organs are available to put a dent in that number. Although dialysis can sustain life for some time, transplantation offers a better quality of life and a longer life for the few individuals who can gain access to transplantation. Each stage of this decedent xenotransplant study approximated the steps that might be taken in a Phase I xenotransplant clinical trial:<\/p>\n<ul type=\"disc\">\n<li>The kidneys were removed from a donor pig housed at a pathogen-free, surgically clean facility. The kidneys were then stored, transported and processed for implantation, just as human kidneys are.<\/li>\n<li>Before surgery, the brain-dead recipient and donor animal underwent a crossmatch compatibility test to determine whether the genetically modified pig kidney and its intended recipient were a good tissue match. A crossmatch is done for every human-to-human kidney transplant; however, this pig-to-human tissue-match test was developed at UAB and marked the first time a prospective crossmatch has been validated between the two species.<\/li>\n<li>The pig kidneys were placed in the exact anatomic locations used for human donor kidneys, with the same attachments to the renal artery, renal vein and the ureter that carries urine from the kidney to the bladder.<\/li>\n<li>The brain-dead recipient received standard immune-suppression therapy used in human-to-human kidney allotransplantation.<\/li>\n<\/ul>\n<p>The study was conducted to meet the standards directly comparable to those that would apply to a Phase I human clinical trial, mirroring every step of a standard transplant between humans. It included Institutional Review Board and Institutional Animal Care and Use Committee approval, a tissue compatibility confirmation before starting the operations, using the standard procedures of human-to-human transplants to remove, preserve, transport and transplant the kidneys into a human, and giving the standard immunosuppression therapy to the recipient.<\/p>\n<p><strong>Transplant recipient Jim Parsons helps open doors to the future of organ transplantation<\/strong><br \/>\nThis scientific and medical breakthrough would not have been possible without Jim Parsons, the recipient, or his family.<\/p>\n<p>Parsons, 57, was a registered organ donor through\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DUcEmaO42CFsZLVXL-K1SCc11apIh5mqBbaxJktArLE_u8ERJgp2tc3n5dRkn2c5Mgg7qKdUgjfFMhrUShU9a4w%3D%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw1MnkYqRiPmMOj2pB1Y_5Kd\"  rel=\"nofollow noreferrer\">Legacy of Hope<\/a>, Alabama\u2019s organ procurement organization, and he had longed to have his organs help others upon his death; but his organs were not suitable for donation. His family permitted UAB to maintain Parsons on a ventilator to keep his body functioning during the study. His native kidneys were removed, and two genetically modified pig kidneys were transplanted.<\/p>\n<p>\u201cMr. Parsons and his family allowed us to replicate precisely how we would perform this transplant in a living human. Their powerful contribution will save thousands of lives, and that could begin in the very near future,\u201d Locke said. \u201cMr. Parsons\u2019 gift honors his legacy and firmly establishes the viability, safety and feasibility of this preclinical model. Because of his gift, we have proposed this to be known as \u2018The Parsons Model.\u2019\u201d<\/p>\n<p>Parsons\u2019 ex-wife, Julie O\u2019Hara, and their children, Ally, David and Cole, made the decision (along with Jim\u2019s sisters and mother) to take part in the study after they were approached by Alan Spriggs with Legacy of Hope and Locke.<\/p>\n<p>\u201cJim was a never-met-a-stranger kind of guy who would talk to anyone and had no enemies \u2014 none,\u201d O\u2019Hara said. \u201cJim would have wanted to save as many people as he could with his death, and if he knew he could potentially save thousands and thousands of people by doing this, he would have had no hesitation. Our dream is that no other person dies waiting for a kidney, and we know that Jim is very proud that his death could potentially bring so much hope to others.\u201d<\/p>\n<p><strong>The critical need for other organ donation options<\/strong><br \/>\nKidney disease kills more people each year than breast or prostate cancer, according to the National Institute of Diabetes and Digestive and Kidney Diseases. Although transplantation is the gold standard treatment for end-stage kidney disease, fewer than 25,000 kidney transplants are performed each year in the United States and 240 Americans on dialysis die every day. Many of these deaths could be prevented if an unlimited supply of kidneys were available for transplant.<\/p>\n<p>The wait for a deceased donor kidney can be as long as five years, and in many states, it is closer to 10 years. Almost 5,000 people per year die waiting on a kidney transplant.<\/p>\n<p><strong>About UAB transplant and the xenotransplant team<\/strong><br \/>\nUAB Medicine is a world leader in organ transplantation and has performed 9,055 kidney transplants from Jan. 1, 1988, to Dec. 31, 2021 \u2014 the second-most kidney transplants in the United States during that time. The focus of UAB\u2019s\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3Dyll2J7kBjDfG86vumy0P5X7Zg96Qzg_gxRQIsDZLVpBsd-QOg5B5xK5XMP-RXkxJ2TRYjXgcUah3uAOHhduyONKFf9knXhDa_7jbHhqEwfvNO4ECFFCcA8c5kL8-zYH9tTsVSbI1FC5rtjVmvcejawWZRWOXOXjC1LRIk9Lnf-0%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw1dTEpsnYDB-1ZboBItwMva\"  rel=\"nofollow noreferrer\">xenotransplantation program<\/a>\u00a0is to address the organ shortage by safely transplanting genetically modified pig kidneys into humans with kidney failure.\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DXssVJrVVYpYguYPPMU_U8M-gOYYDMvPMcMEd6l4QwYSsfRNvwz462R_WqxUdhFdDwdKUBbvsMURD3BI9-ybyxQS0rB9kyOmH1EZBd6gp8zc%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw0f6QMPlFLGVRUQnReIC0ZV\"  rel=\"nofollow noreferrer\">Learn more.<\/a><\/p>\n<p><strong>About UAB<\/strong><br \/>\nKnown for its innovative and interdisciplinary approach to education at both the graduate and undergraduate levels, the University of Alabama at Birmingham,\u00a0a part of the University of Alabama System,\u00a0is an internationally renowned research university and academic medical center. UAB consistently exceeds $600 million in annual research awards and totaled almost $850\u00a0million last year, including one-time COVID-related funding.\u00a0UAB is Alabama\u2019s largest single employer, with more than 26,000 employees, and was named America\u2019s Best Large Employer by Forbes in 2021. The institution\u2019s annual economic impact on the state exceeds $7 billion each year.\u00a0The pillars of UAB\u2019s mission include education, research, innovation and economic development, community engagement, and patient care. Learn more at\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DhAh0KoK9-OSihc9fnnoveBdhg8WbZUw_Y4Xm08weKp8QjWoOIC2D9iiUMF8pOqXMjwd50h1blP3H5oxF9Qyfxw%3D%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw2V_sqqqXYAHiGJ01zDiKHq\"  rel=\"nofollow noreferrer\">www.uab.edu<\/a>.<\/p>\n<p align=\"center\"><strong>EDITOR\u2019S NOTE:<\/strong>\u00a0The\u00a0<strong>University of Alabama at Birmingham<\/strong>\u00a0is one of three doctoral research universities in the University of Alabama System. In your first reference to our institution, please use\u00a0<strong>University of Alabama at Birmingham<\/strong>\u00a0and\u00a0<strong>UAB<\/strong>\u00a0on subsequent references.<\/p>\n<p align=\"center\"><strong>FACEBOOK:\u00a0<\/strong><a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DsQQSlwrNdoqWLoNDZ92T5RDqvQD9KY6KpNzrShIRP2Fy66Je39X6sv8Mg2T_NpH7aL_LU3rJ98w3Bpex90-bg7AEyBmOGOoSdDUQR2Ao2rk%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw2VMdArgEG3CGRPKOUTHPtm\"  rel=\"nofollow noreferrer\">www.facebook.com\/UAB.edu<\/a><strong>\u00a0TEXT:\u00a0<\/strong><a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DhAh0KoK9-OSihc9fnnoveHDwy0MdF4A6Jj_dS-XTa9ZInE03PAf23K-ijvuIxtYrQMUDU1hGGrGzWsbKofxdUQ%3D%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw2EIIXZClUauF4R6JEamFjx\"  rel=\"nofollow noreferrer\"><u>www.uab.edu\/news<\/u><\/a><br \/>\n<strong>TWEETS:\u00a0<\/strong><a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DRO8ZKVLBqVptpXaRsEEqXlGy7jCSt__8apIX7wdkW3BipjSNImKpCjA0MSk_58OGnAfYCh6YjNQb35CbnKa3O_Jz8rf1vi8Ock7bD3sd-Uo%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw187MgRPuWXBoQGN7bGTrqY\"  rel=\"nofollow noreferrer\"><u>www.twitter.com\/uabnews<\/u><\/a>\u00a0<strong>VIDEO:<\/strong>\u00a0<u><a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DJ8KR8WdSmjmKzIhxis0PZuGXIp0z869oEptSfx4wA2RgeSWr05F-S2zfw-mwfjeJUIYEGrEwHj6wBbVHZ6w4pG-q3QANlq-BCwhtUcVMn9Y%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw3mY33EhOzkjV9CQx0z01o6\"  rel=\"nofollow noreferrer\">www.youtube.com\/uabnews<\/a><\/u><\/p>\n<p align=\"left\">Media Contacts:<br \/>\n<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DC02pGN5WVvg7-Z5d1td2WZc4qQsFh2ML2P0pIDS3HXIycvIjJgD7QmbgrzJ-KVkgL-W1i878CQr1AuC4QiWSkw%3D%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw1eG-d7q5wF786QyqYtCowf\"  rel=\"nofollow noreferrer\">Tyler Greer<\/a>, 205-934-2041<br \/>\n<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DR05wWQ2KCRQP2Uo8B9cKFKExUwvBYpJ3p-10fpzmoiVKDuwRBtCiI7DQZZWcGNN-ifwZy457T4A_uaApRzyYRyLrQDlQGu6Vbr3RyNFf1ok%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw09tzqxABKx-jvK5h57k8em\"  rel=\"nofollow noreferrer\">Nicolas Kressmann<\/a>,\u00a0732-532-5318<\/p>\n<p align=\"left\">A photo accompanying this announcement is available at:\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DFa5LwGZSETMsGq7QCT4zvlaneV95FXfROi3Unb2bkl8fVssSTgVFFn-9tOigBKNN2sMpHxE_sO2hkZdPymcqhe8NbDnrvF5MlYtrDLU0gYeYyEYTFiM2Vp0-w9X26kDpsIxRfqdoE_-0tANjImZLqQdsfEVriLdrvPPoFCCUwyyxW9-V0X7l6l19SQm_ElodltUVf-14uG1It8GPzAuIheMXJSQU7NyFLjpoljZvO6plF2l5dnh_KiOd-WJERZ9Jw6ZSAfoG1QldOM1zl0BLJA%3D%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw0CvIXtOINIKGD2-2vCtpUl\"  rel=\"nofollow noreferrer\">https:\/\/www.globenewswire.<wbr \/>com\/NewsRoom\/AttachmentNg\/<wbr \/>33d4e6ff-7c94-45e9-b4b2-<wbr \/>54b02013eabc<\/a><\/p>\n<p align=\"left\">A\u00a0video accompanying this announcement is available at:\u00a0<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.globenewswire.com\/Tracker?data%3DFa5LwGZSETMsGq7QCT4zvlaneV95FXfROi3Unb2bkl8fVssSTgVFFn-9tOigBKNN-pygluEf5eRetZiAt43S_sma6Af1MX3owHhGO99Un9QqdacFYl_TRkXzIZA006nZ5H4fLqajFdZqE_Yp3dw7bhtKGtbLkpU0GdMEAbOGCk-Ear7V_rujgJeFiaiuK2RK2zD1HXF0ydtnfehgX3asQjVluW4Rvx8wdgk8socbMXLv1M3R8en26XyWkjaIBdligdkHlOCrSwtARTOOXGODIA%3D%3D&amp;source=gmail-html&amp;ust=1642767299194000&amp;usg=AOvVaw1Mcl6Lhr5eEg0iLns2ugHN\"  rel=\"nofollow noreferrer\">https:\/\/www.globenewswire.<wbr \/>com\/NewsRoom\/AttachmentNg\/<wbr \/>90656f74-a325-479f-9177-<wbr \/>9d9538f11799<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>UAB announces the first clinical-grade transplant of gene-edited pig kidneys into brain-dead human NEWS HIGHLIGHTS UAB researchers have achieved several world\u2019s firsts with pig-to-human kidney transplant: First peer-reviewed\/published\u00a0study of a genetically modified pig kidney transplanted into the body of a brain-dead human recipient First such study on a pig-to-human kidney transplant using genetically modified kidneys [\u2026]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human - Myanmar Newswire<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human - Myanmar Newswire\" \/>\n<meta property=\"og:description\" content=\"UAB announces the first clinical-grade transplant of gene-edited pig kidneys into brain-dead human NEWS HIGHLIGHTS UAB researchers have achieved several world\u2019s firsts with pig-to-human kidney transplant: First peer-reviewed\/published\u00a0study of a genetically modified pig kidney transplanted into the body of a brain-dead human recipient First such study on a pig-to-human kidney transplant using genetically modified kidneys [\u2026]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/\" \/>\n<meta property=\"og:site_name\" content=\"Myanmar Newswire\" \/>\n<meta property=\"article:published_time\" content=\"2022-01-20T12:16:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\/\/myanmarnewswire.com\/#\/schema\/person\/f449613780cb879df549f28a5d10715b\"},\"headline\":\"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human\",\"datePublished\":\"2022-01-20T12:16:12+00:00\",\"dateModified\":\"2022-01-20T12:16:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/\"},\"wordCount\":1995,\"publisher\":{\"@id\":\"https:\/\/myanmarnewswire.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png\",\"articleSection\":[\"Press Releases\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/\",\"url\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/\",\"name\":\"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human - Myanmar Newswire\",\"isPartOf\":{\"@id\":\"https:\/\/myanmarnewswire.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png\",\"datePublished\":\"2022-01-20T12:16:12+00:00\",\"dateModified\":\"2022-01-20T12:16:12+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage\",\"url\":\"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png\",\"contentUrl\":\"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/myanmarnewswire.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Press Releases\",\"item\":\"https:\/\/myanmarnewswire.com\/category\/press-releases\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/myanmarnewswire.com\/#website\",\"url\":\"https:\/\/myanmarnewswire.com\/\",\"name\":\"Myanmar Newswire\",\"description\":\"Latest News, Right Away!\",\"publisher\":{\"@id\":\"https:\/\/myanmarnewswire.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/myanmarnewswire.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/myanmarnewswire.com\/#organization\",\"name\":\"Myanmar Newswire\",\"url\":\"https:\/\/myanmarnewswire.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/myanmarnewswire.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/myanmarnewswire.com\/wp-content\/uploads\/2017\/08\/logo-2.png\",\"contentUrl\":\"https:\/\/myanmarnewswire.com\/wp-content\/uploads\/2017\/08\/logo-2.png\",\"width\":400,\"height\":54,\"caption\":\"Myanmar Newswire\"},\"image\":{\"@id\":\"https:\/\/myanmarnewswire.com\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/myanmarnewswire.com\/#\/schema\/person\/f449613780cb879df549f28a5d10715b\",\"name\":\"admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/myanmarnewswire.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ff4aa10d4f36ab9dc3cce9e101792273?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ff4aa10d4f36ab9dc3cce9e101792273?s=96&d=mm&r=g\",\"caption\":\"admin\"},\"url\":\"https:\/\/myanmarnewswire.com\/author\/admin\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human - Myanmar Newswire","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/","og_locale":"en_US","og_type":"article","og_title":"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human - Myanmar Newswire","og_description":"UAB announces the first clinical-grade transplant of gene-edited pig kidneys into brain-dead human NEWS HIGHLIGHTS UAB researchers have achieved several world\u2019s firsts with pig-to-human kidney transplant: First peer-reviewed\/published\u00a0study of a genetically modified pig kidney transplanted into the body of a brain-dead human recipient First such study on a pig-to-human kidney transplant using genetically modified kidneys [\u2026]","og_url":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/","og_site_name":"Myanmar Newswire","article_published_time":"2022-01-20T12:16:12+00:00","og_image":[{"url":"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png"}],"author":"admin","twitter_card":"summary_large_image","twitter_misc":{"Written by":"admin","Est. reading time":"10 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#article","isPartOf":{"@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/"},"author":{"name":"admin","@id":"https:\/\/myanmarnewswire.com\/#\/schema\/person\/f449613780cb879df549f28a5d10715b"},"headline":"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human","datePublished":"2022-01-20T12:16:12+00:00","dateModified":"2022-01-20T12:16:12+00:00","mainEntityOfPage":{"@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/"},"wordCount":1995,"publisher":{"@id":"https:\/\/myanmarnewswire.com\/#organization"},"image":{"@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage"},"thumbnailUrl":"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png","articleSection":["Press Releases"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/","url":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/","name":"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human - Myanmar Newswire","isPartOf":{"@id":"https:\/\/myanmarnewswire.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage"},"image":{"@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage"},"thumbnailUrl":"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png","datePublished":"2022-01-20T12:16:12+00:00","dateModified":"2022-01-20T12:16:12+00:00","breadcrumb":{"@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#primaryimage","url":"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png","contentUrl":"https:\/\/ci5.googleusercontent.com\/proxy\/xRezzxJ3HWSAJ5yLY1wBPDhU35qEHN7OgDmcNH7aSLdx1weyICng3nIInzsEXKFO4n8d7whx_90oVMMZ45En_0Ria7AYr9ytpA5U8_Bv8qKSReIgPBL0FggCiX8V7rWUHGJWubcnWBTATCxk1sxdwPZczsTLBZWarmoDBx95ar7Rofbf91_-dDZXM-D1IE5y5pB_4mE_ApyfOrFDS-n1m-rDKg=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/33d4e6ff-7c94-45e9-b4b2-54b02013eabc\/medium\/uab-announces-the-first-clinical-grade-transplant-of-gene-ed.png"},{"@type":"BreadcrumbList","@id":"https:\/\/myanmarnewswire.com\/uab-announces-first-clinical-grade-transplant-of-gene-edited-pig-kidneys-into-brain-dead-human\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/myanmarnewswire.com\/"},{"@type":"ListItem","position":2,"name":"Press Releases","item":"https:\/\/myanmarnewswire.com\/category\/press-releases\/"},{"@type":"ListItem","position":3,"name":"UAB announces first clinical-grade transplant of gene-edited pig kidneys into brain-dead human"}]},{"@type":"WebSite","@id":"https:\/\/myanmarnewswire.com\/#website","url":"https:\/\/myanmarnewswire.com\/","name":"Myanmar Newswire","description":"Latest News, Right Away!","publisher":{"@id":"https:\/\/myanmarnewswire.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/myanmarnewswire.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/myanmarnewswire.com\/#organization","name":"Myanmar Newswire","url":"https:\/\/myanmarnewswire.com\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/myanmarnewswire.com\/#\/schema\/logo\/image\/","url":"https:\/\/myanmarnewswire.com\/wp-content\/uploads\/2017\/08\/logo-2.png","contentUrl":"https:\/\/myanmarnewswire.com\/wp-content\/uploads\/2017\/08\/logo-2.png","width":400,"height":54,"caption":"Myanmar Newswire"},"image":{"@id":"https:\/\/myanmarnewswire.com\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/myanmarnewswire.com\/#\/schema\/person\/f449613780cb879df549f28a5d10715b","name":"admin","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/myanmarnewswire.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/ff4aa10d4f36ab9dc3cce9e101792273?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ff4aa10d4f36ab9dc3cce9e101792273?s=96&d=mm&r=g","caption":"admin"},"url":"https:\/\/myanmarnewswire.com\/author\/admin\/"}]}},"_links":{"self":[{"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/posts\/20793"}],"collection":[{"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/comments?post=20793"}],"version-history":[{"count":0,"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/posts\/20793\/revisions"}],"wp:attachment":[{"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/media?parent=20793"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/categories?post=20793"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/myanmarnewswire.com\/wp-json\/wp\/v2\/tags?post=20793"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}